July 8-12, 2006

University of Mississippi, Oxford, Mississippi 

Program and Abstracts (PDF)

Saturday, July 8^th

1:00 – 6:00 PM            Registration (Yerby Conference Center Foyer)

4:00 – 6:00 PM             PSNA Executive Committee Meeting (Yerby Conference Center)

6:00 – 9:00 PM            Wine Mixer (Memory House)

Sunday, July 9^th

Session I – Natural Product Synthesis and Biosynthesis, Part 1 (Chair: Clint Chapple)

8:00 – 8:10 AM            Daneel Ferreira (University of Mississippi) – Opening Remarks

8:10 – 8:20 AM            Alice Clark, UM Vice Chancellor for Research and Sponsored Programs – Welcome

8:20 – 9:00 AM            Invited: Norman Lewis (Washington State University) – Plant phenolics in health-protection, disease treatment and plant growth/development: Biochemistry/structural biology of their formation

9:00 – 9:30 AM            Neish: Steven Ralph , Joseph W. Hudgins, Sharon Jancsik, Lina L. Madilao and Jörg Bohlmann (University of British Columbia) – Functional genomics approaches to characterize the contribution of phenolic secondary metabolites to insect induced defenses in conifer trees

9:30 – 9:50 AM            Contributed: Georg G. Gross (Universität Ulm) – Biosynthesis of hydrolysable tannins – Unraveled by enzyme studies

9:50 – 10:10 AM            Contributed: Wei-Li Yang and Mark A. Bernards (The University of Western Ontario) – Aliphatic carbon flux analysis during wound-induced suberization

10:10 – 10:25 AM            Break

10:25 – 11:15 AM            Invited: Toni M. Kutchan (Leibniz Institute of Plant Biochemistry) – Plant natural products biosynthesis – Recent progress with alkaloids derived from dopamine

11:15 – 11:35 AM            Contributed: Dylan Levac, Jun Murata and Vincenzo De Luca (Brock University) – Differential extraction of leaf epidermal enzymes by carborundum abrasion technique to purify, characterize and clone tabersonine 16-O-methyltransferase from Catharanthus roseus

11:35 – 11:55 AM            Contributed: Daniel G. Vassão¹, David R. Gang², Eran Pichersky³, Laurence B. Davin¹ and Norman G. Lewis¹ (¹Washington State University, ²University of Arizona, and ³University of Michigan) Biosynthesis of phenolic flavor compounds in basil (Ocimum basilicum)

11:55 – 12:15 PM            Contributed: Jack W. Blount¹, Luzia Modolo¹, Lahoucine Achnine^{1, 2}, and Richard A. Dixon¹ (¹The Samuel Roberts Noble Foundation and ²GenApps, Inc.) – A comparative study of Medicago truncatula glycosyltransferases involved in flavonoid and isoflavonoid biosynthesis

12:15 – 1:30 PM            Lunch Provided at Yerby

Session II – Natural Product Isolation, Structure Elucidation, and Methods for Analysis (Chair: Charles Cantrell)

1:30 – 2:10 PM            Invited: William F. Reynolds (University of Toronto) Overcoming Problems in Natural Product Elucidation by NMR

2:10 -- 2:50 PM Neish: Xing-Cong Li, Yuanqing Ding, and Daneel Ferreira (University of Mississippi) -- Absolute configuration and conformation of bioactive 3,8"-biflavononoids

2:30 – 2:50 PM            Contributed: Jayaprakash, G. K.,¹ Mandadi, K.K.¹, Jadegoud, Y.², Nagana Gowda, G.A.² and Bhimanagouda S. Patil¹ (¹Texas A & M University and ² Centre of Biomedical Magnetic Resonance) – Unique anticancer limonoids from Citrus aurantium

2:50 – 3:20 PM            Break

3:20 – 4:00 PM            Invited: Rachel Mata, Sergio Martínez-Luis, Araceli Pérez-Vásquez and Rogelio Rodríguez. (Universidad Nacional Autónoma de México) – Natural phytotoxins with calmodulin inhibitor properties

4:00 – 4:20 PM            Contributed: Amit Vikram, G. K. Jayaprakash, and Bhimanagouda S. Patil (Texas A & M University) – Simultaneous Separation of Health Promoting bioactive citrus limonoids and their glucosides

4:20 – 4:40 PM            Contributed: Lenong Li, Luzia Modolo, Richard A. Dixon, and Xiaoqiang Wang (Samuel Roberts Noble Foundation) – Crystal structure of a new uridine diphosphate glycosyltransferase from Medicago truncatula

4:40 – 5:00 PM            Contributed: Zulfiqar Ali,¹ Shabana I. Khan,¹ Daneel Ferreira,² and Ikhlas A. Khan^1,2 (University of Mississippi) – Podocarpaside K, an arabinoside possessing a novel triterpenoid triterpenoid backbone from Actaea podocarpa

5:00 – 7:00 PM            Business Meeting

Monday, July 10^th

Session III – Natural Product Synthesis and Biosynthesis, Part 2 (Chair: Daneel Ferreira)

8:20 – 9:00 AM            Invited: David G. I. Kingston (Virginia Polytechnic Institute and State University) – The Shape of Things to Come: Structural and Synthetic Studies of Taxol and Related Compounds

9:00 – 9:20 AM            Contributed: Jannie P. J. Marais and Daneel Ferreira (University of Mississippi) Synthesis of A-type proanthocyanidins

9:20 – 9:40 AM            Contributed: Oliver R. A. Corea^1,2, Man-Ho Cho¹, Aldwin M. Anterola¹, Frances Anne Moog-Anterola¹, Susanne E. Kohalmi², Mark A. Bernards², Laurence B. Davin¹ and Norman G. Lewis¹ (¹Washington State University and ²University of Western Ontario) Phenylalanine biosynthesis in Arabidopsis thaliana: Identification and characterization of arogenate dehydratase(s)

9:40 – 10:10 AM            Neish: Meimei Xu, Sladjana Prisic, Dana Morrone, Ross Wilderman, & Reuben J. Peters (Iowa State University) Gibberellins and beyond!

10:10 – 10:25 AM            Break

10:25 – 11:15 AM            Invited: Mitch Avery (University of Mississippi) - title

11:15 – 11:35 AM            Contributed: Mary Magnotta, Jun Murata, Jianxin Chen and Vincenzo De Luca (Brock University) – Identification of a low vindoline accumulating cultivar of Catharanthus roseus (L.) G. Don by monoterpenoid indole alkaloid and enzymatic profiling

11:35 – 11:55 AM            Contributed: Syed G. A. Moinuddin, Michaël Jourdes, Laurence B. Davin and Norman G. Lewis (Washington State University) Towards defining interunit linkages sequences in lignin primary structure

11:55 – 12:15 PM            Contributed: Kye-Won Kim, Syed G. A. Moinuddin, ChulHee Kang, Laurence B. Davin and Norman G. Lewis (Washington State University) Towards defining the molecular basis of differing enantiospecificities of pinoresinol-lariciresinol reductases in western red cedar using site-directed mutagenesis

12:15 – 1:30 PM            Box Lunch Provided at Yerby

Session IV – Discovery and Development of Natural Products for Pest Management (Chair: Franck Dayan)

1:30 – 2:10 PM            Invited: S. Textor, J-W. de Kraker, J. Tokuhisa, M. Reichelt, J. Gershenzon (Max Planck Institute for Chemical Ecology) – Engineering Plant and Chemical Defense for Managing Insect Pests: Lessons from Arabidopsis

2:10 – 2:30 PM            Contributed: Raymond Thomas¹, Alice Fang², Carol A. Peterson², Terry R. Anderson³ and Mark A. Bernards¹ (¹The University of Western Ontario, ²University of Waterloo and ³Agriculture and Agri-Food Canada) – Suberin as a determinate of Phytophthora resistance in soybean

2:30 – 2:50 PM            Contributed: C. Bertin, F. C. Schroeder, L. A. Weston (Cornell University) – Towards a new bioherbicide in turf settings?

2:50 – 3:20 PM            Break

3:20 – 4:00 PM            Invited: Stephen O. Duke, Franck E. Dayan, David E. Wedge, Agnes M. Rimando, Charles L. Cantrell, Kevin K. Schrader, Zhiqiang Pan, Scott R. Baerson, Nurhayat Tabanca, and Kumudini Meepagala (USDA, ARS) – Discovery and Development of Natural Products for Pest Management

4:00 – 4:20 PM            Contributed: Eric T. Johnson, Mark A. Berhow and Patrick F. Dowd (USDA-ARS) – P1-mediated transgenic secondary metabolite production in corn silks moderately enhances insect resistance

4:20 – 4:40 PM            Contributed: Audrey Sauldubois¹, Charles L. Cantrell², Stephen O. Duke², and Franck E. Dayan².  (¹Université d’Angers, FRANCE and ²USDA-ARS, Natural Products Utilization Research Unit) – p-Hydroxyphenylpyruvate Dioxygenase is a Target Site for β-Triketone Phytochemicals

6:00 – 9:00 PM            Poster Session (National Center for Natural Products Research)

Tuesday, July 11^th

Session V – Metabolic Engineering of Natural Products (Chair: Daniel Cook)

8:20 – 9:00 AM            Invited: David Gang (University of Arizona) – Control of aromatic metabolism in sweet basil

9:00 – 9:20 AM            Contributed: Jim Brandle, Alex Richman, Tania Humphrey, Ralph Chapman and Brian McGarvey  (Agriculture and AgriFood Canda) – Identification, isolation and characterization of five steps in the synthesis of the sweet glycosides of Stevia rebaudiana using functional genomics

9:20 – 9:40 AM            Contributed: Xiao-Hong Yu¹, Richard A. Dixon² and Chang-Jun Liu¹ (¹Brookhaven National Laboratory and ² the Noble Foundation) – Genome-wide characterization of acyl-CoA dependent acyltransferases responsible for (iso)flavonoid biosynthesis

9:40 – 10:10 AM            Neish: Catherine Loncaric, Amanda Ward, and Kevin D. Walker (Michigan State University) – Evaluating the Biogenesis and Molecular Pathways of Bioactive Plant Products

10:10 – 10:30 AM            Break

10:30 – 11:10 AM            Invited: Sanja Roje (Washington State University) – Exploring and engineering plant one-carbon and folate metabolism

11:10 – 11:30 AM            Contributed: Argelia Lorence¹, Bonnie J. Woffenden², Luis Nopo-Olazabal¹, Javier Martínez¹, Craig L. Nessler², and Fabricio Medina-Bolivar¹ (¹Arkansas State University and ²Virginia Tech) Enhanced production of specialized metabolites in tobacco over-expressing an AP2-type transcription factor

 11:30 -- 11:50 AM Contributed: David J. Schultz 1,2 and Oliver W. Starks 1 (1University of Louisville and 2 University of Louisville School of Medicine) -- EST database approach to identify anacardic acid biosynthesis genes

11:50 – 1:30 PM            Lunch Provided at Yerby

6:00 – 9:00 PM             Banquet with Jones Sisters as entertainers (Oxford University Club)

Wednesday, July 12^th

Session VI – Herbal Products and Nutraceuticals (Chair: Daneel Ferreira)

8:20 – 9:00 AM            Invited: Mahmoud ElSohly (University of Mississippi) – Marijuana Project at the University of Mississippi

9:00 – 9:20 AM            Contributed: Keat T. Teoh, Devin R. Polichuk, Darwin W. Reed, Goska Nowak and Patrick S. Covello (Plant Biotechnology Institute) – Functional genomics and the biosynthesis of artemisinin

9:20 – 10:00 AM            Invited: Ikhlas Khan (University of Mississippi) – Marker compounds and beyond

10:00 – 10:30 AM            Break

10:30 – 11:10 AM            Invited: James D. McChesney (Tapestry Pharmaceuticals, Inc. and Chromadex Analytics, Inc.) – Natural Products: Back to the Future or Into Extinction?

11:10 – 11:40 AM Neish: Fabricio Medina-Bolivar^1,2,4, John Hubstenberger¹, Jose Condori¹, Sean O’Keefe³, Selester Bennett⁴ and Maureen Dolan^1,4. (¹Arkansas Biosciences Institute, ²Arkansas State University, ³Virginia Tech and ⁴Nature West Inc.) – Resveratrol production in hairy roots of peanut

11:40 – 12:00 AM            Contributed: Christina M. Coleman,¹ Daneel Ferreira,¹ Amy B. Howell,² Jess D. Reed,³ Christian G. Krueger³ and Jannie P. J. Marais⁴ (¹ University of Mississippi, ² Rutgers University, ³ University of Wisconsin, and ⁴ National Center for Natural Products Research) Bioactive metabolites of cranberry juice

12:20 – 1:40 PM            Box Lunch Provided at Yerby

Organizing Committee Members